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navigation links             | ... | Full PubMed List of Publications by V.N. KewalRamani
Krishnan,
L., Matreyek, K., Oztop, I., Lee, K., Tipper, C.H., Li, X., Dar, M.J., KewalRamani,
V.N., and Engelman, A. (2009) The requirement for cellular transportin-3
(TNPO3/TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid
and not integrase. J. Virol., in press (Oct 21 Epub ahead of print). Chung,
N.P.Y., Breun, S.K.J., Bashirova, A., Baumann, J.G., Martin, T.D., Karamchandani,
J.M., Rausch, J.W., Le Grice, S.F.J., Wu, L., Carrington, M., and KewalRamani,
V.N. (2009) HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing
nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition
domain that are absent in liver/lymph node-SIGN (L-SIGN). J. Biol. Chem.,
in press (Oct 15 Epub ahead of print). Hatziioannou,
T., Ambrose, Z., Chung, N.P.Y., Piatak, M., Jr., Yuan, F., Trubey, C.M., Coalter,
V., Kiser, R., Schneider, D., Smedley, J., Pung, R., Gathuka, M., Estes, J.D.,
Veazey, R.S., KewalRamani, V.N., Lifson, J.D., and Bieniasz, P.D.
(2009) A macaque model of HIV-1 infection. Proc. Natl. Acad. Sci.
USA 106: 4425-4429. Ambrose,
Z., and KewalRamani, V.N. (2008) Of mice and monkeys: New advances
in animal models to study HIV-1 therapy and prophylaxis. Future HIV Ther.
2: 363-373. Ambrose,
Z., Compton, L., Piatak, M., Jr., Lu, D., Alvord, W.G., Lubomirski, M.S., Hildreth,
J.E.K., Lifson, J.D., Miller, C.J., and KewalRamani, V.N. (2008)
Incomplete protection against simian immunodeficiency virus vaginal transmission
in rhesus macaques by a topical antiviral agent revealed by repeat challenges.
J. Virol. 82: 6591-6599. Mulky, A., Cohen, T.V., Kozlov, S.V., Korbei, B., Foisner, R., Stewart, C.L., and KewalRamani, V.N. (2008) The LEM domain proteins emerin and LAP2a are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections. J. Virol. 82: 5860-5868. [Abstract] [Full-text PDF article] Ambrose,
Z., Palmer, S., Boltz, V.F., Kearney, M., Larsen, K., Polacino, P., Flanary, L.,
Oswald, K., Piatak, M., Jr., Smedley, J., Shao, W., Bischofberger, N., Maldarelli,
F., Kimata, J.T., Mellors, J.W., Hu, S.-L., Coffin, J.M., Lifson, J.D., and KewalRamani,
V.N. (2007) Suppression of viremia and evolution of human immunodeficiency
virus type 1 drug resistance in a macaque model for antiretroviral therapy.
J. Virol. 81: 12145-12155. Ambrose,
Z., KewalRamani, V.N., Bieniasz, P.D., and Hatziioannou, T. (2007)
HIV/AIDS: In search of an animal model. Trends Biotechnol. 25: 333-337.
Wang, J.-H., Janas, A.M., Olson, W.J., KewalRamani, V.N., and Wu, L. (2007) CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1. J. Virol. 81: 2497-2507. [Abstract] [Full-text PDF article] Wu, L., and KewalRamani, V.N. (2006) Dendritic-cell interactions with HIV: Infection and viral dissemination. Nat. Rev. Immun. 6: 859-868. [Abstract] [Full-text PDF article] Ambrose,
Z., Julias, J.G., KewalRamani, V.N., and Hughes, S.H. (2006)
The level of reverse transcriptase (RT) in human immunodeficiency virus type 1
particles affects susceptibility to nonnucleoside RT inhibitors but not to lamivudine.
J. Virol. 80: 2578-2581. Sun, J., Soos, T., KewalRamani, V.N., Osiecki, K., Zheng, J.H., Falkin, L., Santambrogio, L., Littman, D.R., and Goldstein, H. (2006) CD4-specific transgenic expression of human cyclin T1 markedly increases human immunodeficiency virus type 1 (HIV-1) production by CD4+ T lymphocytes and myeloid cells in mice transgenic for a provirus encoding a monocyte-tropic HIV-1 isolate. J. Virol. 80: 1850-1862. [Abstract] [Full-text PDF article] Garcia-Pineres,
A.J., Hildesheim, A., Trivett, M., Williams, M., Wu, L., KewalRamani, V.N.,
and Pinto, L.A. (2006) Role of DC-SIGN in the activation of dendritic
cells by HPV-16 L1 virus-like particle vaccine. Eur. J. Immunol. 36: 437-445.
VanCompernolle, S.E., Taylor, R.J., Oswald-Richter, K., Jiang, J., Youree, B.E., Bowie, J.H., Tyler, M.J., Conlon, J.M., Wade, D., Aiken, C., Dermody, T.S., KewalRamani, V.N., Rollins-Smith, L.A., and Unutmaz, D. (2005) Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells. J. Virol. 79: 11598-11606. [Abstract] [Full-text PDF article] Ambrose, Z., Boltz, V., Palmer, S., Coffin, J.M., Hughes, S.H., and KewalRamani, V.N. (2004) In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques. J. Virol. 78: 13553-13561. [Abstract] [Full-text PDF article] Baumann,
J.G., Unutmaz, D., Miller, M.D., Breun, S.K.J., Grill, S.M., Mirro, J., Littman,
D.R., Rein, A., and KewalRamani, V.N. (2004) Murine T cells
potently restrict human immunodeficiency virus infection. J. Virol. 78:
12537-12547. Lee,
K., and KewalRamani, V.N. (2004) In defense of the cell: TRIM5a
interception of mammalian retroviruses. Proc. Natl. Acad. Sci. USA 101:
10496-10497. Wu, L., Martin, T.D., Han, Y.-C., Breun, S.K.J., and KewalRamani, V.N. (2004) Trans-dominant cellular inhibition of DC-SIGN-mediated HIV-1 transmission. Retrovirology 1: 14 (Epub). [PubMed citation] [Full-text PDF article] Wu,
L., Martin, T.D., Carrington, M., and KewalRamani, V.N. (2004) Raji B
cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission.
Virology 318: 17-23. KewalRamani, V.N., and Coffin, J.M. (2003) Weapons of mutational destruction. Science 301: 923-925. [PubMed citation] [Full-text PDF article] McDonald,
D., Wu, L., Bohks, S.M., KewalRamani, V.N., Unutmaz, D., and Hope, T.J.
(2003) Recruitment of HIV and its receptors to dendritic cell-T cell junctions.
Science 300: 1295-1297. Wu,
L., Martin, T.D., Vazeux, R., Unutmaz, D., and KewalRamani, V.N. (2002)
Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions
with ICAM-3 do not promote human immunodeficiency virus type 1 transmission.
J. Virol. 76: 5905-5914. Wu, L., Bashirova, A.A., Martin, T.D., Villamide, L., Mehlhop, E., Chertov, A.O., Unutmaz, D., Pope, M., Carrington, M., and KewalRamani, V.N. (2002) Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN. Proc. Natl. Acad. Sci. USA 99:1568-1573. [Abstract] [Full-text PDF article] Bashirova,
A.A., Geijtenbeek, T.B., van Duijnhoven, G.C., van Vliet, S.J., Eilering, J.B.,
Martin, M.P., Wu, L., Martin, T.D., Viebig, N., Knolle, P.A., KewalRamani,
V.N., van Kooyk, Y., and Carrington, M. (2001) A dendritic cell-specific
intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein
is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1
infection. J. Exp. Med. 193:671-678. Geijtenbeek, T.B., Kwon, D.S., Torensma, R., van Vliet, S.J., van Duijnhoven, G.C., Middel, J., Cornelissen, I.L., Nottet, H.S., KewalRamani, V.N., Littman, D.R., Figdor, C.G., and van Kooyk, Y. (2000) DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100: 587-597. [Abstract] [Full-text PDF article] Unutmaz, D., KewalRamani, V.N., Marmon, S., and Littman, D.R. (1999) Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes. J. Exp. Med. 189: 1735-1746. [Abstract] [Full-text PDF article*] Garber, M.E., Wei, P., KewalRamani, V.N., Mayall, T.P., Herrmann, C.H., Rice, A.P., Littman, D.R., and Jones, K.A. (1998) The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes Dev. 12: 3512-3527. [Abstract] [Full-text PDF article§] Deng, H.-K., Unutmaz, D., KewalRamani, V.N., and Littman, D.R. (1997) Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 388: 296-300. [Abstract] [Full-text PDF article] KewalRamani, V.N., and Emerman, M. (1996) Vpx association with mature core structures of HIV-2. Virology 218: 159-168. [Abstract] [Full-text PDF article] KewalRamani, V.N., Panganiban, A.T., and Emerman, M. (1992) Spleen necrosis virus, an avian immunosuppressive retrovirus, shares a receptor with the type D simian retroviruses. J. Virol. 66: 3026-3031. [Abstract] [Full-text PDF article] * Reproduced from The Journal of Experimental Medicine, 1999, Vol. 189, pp. 1735-1746 by copyright permission of The Rockefeller University Press. §
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