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The following are publications on retroviral vectors by the Hughes laboratory:
Reduced
genotoxicity of avian sarcoma leukosis virus vectors in rhesus
long-term repopulating
cells compared to standard murine retrovirus vectors.
Mol Ther. 2008 Jun 24. [Epub ahead of print]
PMID: 18578011
[PubMed - as supplied by publisher]
- The
effects of alternate polypurine tracts (PPTs) and mutations of sequences
adjacent
to the PPT on viral replication and cleavage specificity of the Rous
sarcoma
virus reverse transcriptase.
J Virol. 2008 Jun 18. [Epub ahead of print]
PMID: 18562520
[PubMed - as supplied by publisher]
- Mutations
in the human immunodeficiency virus type 1 polypurine tract (PPT)
reduce the
rate of PPT cleavage and plus-strand DNA synthesis.
J Virol. 2008 May;82(10):5104-8.
PMID:
18321979 [PubMed - indexed for MEDLINE]
- Mutations
in the U5 region adjacent to the primer binding site affect tRNA
cleavage by
human immunodeficiency virus type 1 reverse transcriptase in vivo.
J Virol.
2008 Jan;82(2):719-27.
PMID: 17989171 [PubMed - indexed for MEDLINE]
- Rous
sarcoma virus (RSV) integration in vivo: a CA dinucleotide is not required
in
U3, and RSV linear DNA does not autointegrate.
J Virol. 2008 Jan;82(1):503-12.
PMID:
17959663 [PubMed - indexed for MEDLINE]
- Transduction
of rhesus macaque hematopoietic stem and progenitor cells with
avian sarcoma
and leukosis virus vectors.
Hum Gene Ther. 2007 Aug;18(8):691-700.
PMID:
17655493 [PubMed - indexed for MEDLINE]
- Analysis
of amino acids in the beta7-beta8 loop of human immunodeficiency
virus type
1 reverse transcriptase for their role in virus replication.
J Mol Biol. 2007
Feb 2;365(5):1368-78.
PMID: 17141805 [PubMed - indexed for MEDLINE]
- Alternate
polypurine tracts affect rous sarcoma virus integration in vivo.
J Virol. 2006
Oct;80(20):10281-4.
PMID: 17005708 [PubMed - indexed for MEDLINE]
- Combining
mutations in HIV-1 reverse transcriptase with mutations in the
HIV-1 polypurine
tract affects RNase H cleavages involved in PPT utilization.
Virology. 2006
May 10;348(2):378-88.
PMID: 16473384 [PubMed - indexed for MEDLINE]
- Mutations
in the U5 sequences adjacent to the primer binding site do not
affect tRNA
cleavage by rous sarcoma virus RNase H but do cause aberrant
integrations in
vivo.
J Virol. 2006 Jan;80(1):451-9.
PMID: 16352569 [PubMed - indexed for
MEDLINE]
- In
vitro analysis of the effects of mutations in the G-tract of the human
immunodeficiency
virus type 1 polypurine tract on RNase H cleavage specificity.
Virology. 2007
Apr 10;360(2):341-9.
PMID: 17123564 [PubMed - indexed for MEDLINE]
- Alternate
polypurine tracts (PPTs) affect the rous sarcoma virus RNase H
cleavage specificity
and reveal a preferential cleavage following a GA
dinucleotide sequence at
the PPT-U3 junction.
J Virol. 2005 Nov;79(21):13694-704.
PMID: 16227289
[PubMed - indexed for MEDLINE]
- Mutations
of a residue within the polyproline-rich region of Env alter the
replication
rate and level of cytopathic effects in chimeric avian retroviral vectors.
J
Virol. 2005 Aug;79(16):10258-67.
PMID: 16051819 [PubMed - indexed for MEDLINE]
- Effects
of mutations in the G tract of the human immunodeficiency virus
type 1 polypurine
tract on virus replication and RNase H cleavage.
J Virol. 2004 Dec;78(23):13315-24.
PMID:
15542682 [PubMed - indexed for MEDLINE]
- The
RCAS vector system.
Folia Biol (Praha). 2004;50(3-4):107-19. Review. No abstract
available.
PMID: 15373344 [PubMed - indexed for MEDLINE]
- Identification
of glycosylation sites in the SU component of the avian
sarcoma/leukosis virus
envelope glycoprotein (subgroup A) by mass spectrometry.
Virology. 2004 Aug
15;326(1):171-81.
PMID: 15262505 [PubMed - indexed for MEDLINE]
- Mutations
at position 184 of human immunodeficiency virus type-1 reverse
transcriptase
affect virus titer and viral DNA synthesis.
Virology. 2004 Apr 25;322(1):13-21.
PMID:
15063112 [PubMed - indexed for MEDLINE]
- Mutations
in the 5' end of the human immunodeficiency virus type 1
polypurine tract affect
RNase H cleavage specificity and virus titer.
J Virol. 2003 Oct;77(20):11150-7.
PMID:
14512562 [PubMed - indexed for MEDLINE]
- Mutation
of amino acids in the connection domain of human immunodeficiency virus
type
1 reverse transcriptase that contact the template-primer affects RNase H activity.
J
Virol. 2003 Aug;77(15):8548-54.
PMID: 12857924 [PubMed - indexed for MEDLINE]
- Mutations
in the RNase H domain of HIV-1 reverse transcriptase affect the
initiation
of DNA synthesis and the specificity of RNase H cleavage in vivo.
Proc Natl
Acad Sci U S A. 2002 Jul 9;99(14):9515-20.
PMID: 12093908 [PubMed - indexed
for MEDLINE]
- Construction
and characterization of a replication-competent retroviral
shuttle vector plasmid.
J Virol. 2002 Feb;76(4):1762-1768.
PMID: 11799171 [PubMed
- as supplied by publisher]
- Adaptation
of chimeric retroviruses in vitro and in vivo: Isolation of avian
retroviral
vectors with extended host range.
J Virol. 2001 Jun 1;75(11):4973-4983.
PMID: 11333876 [PubMed
- as supplied by publisher]
- Restricting
expression prolongs expression of foreign genes introduced into
animals by
retroviruses.
J Virol. 2000 Nov;74(21):10202-6.
PMID: 11024149 [PubMed -
indexed for MEDLINE]
- Soluble
forms of the subgroup A avian leukosis virus [ALV(A)] receptor Tva
significantly
inhibit ALV(A) infection in vitro and in vivo.
J Virol. 1999 Dec;73(12):10051-60.
PMID:
10559319 [PubMed - indexed for MEDLINE]
- Studies
of the genomic RNA of leukosis viruses: implications for RNA dimerization.
J
Virol. 1999 Sep;73(9):7165-74.
PMID: 10438803 [PubMed - indexed for MEDLINE]
- An
avian sarcoma/leukosis virus-based gene trap vector for mammalian cells.
J
Virol. 1999 Aug;73(8):6946-52.
PMID: 10400793 [PubMed - indexed for MEDLINE]
- The
EV-O-derived cell line DF-1 supports the efficient replication of
avian leukosis-sarcoma
viruses and vectors.
Virology. 1998 Sep 1;248(2):305-11.
PMID: 9721239 [PubMed
- indexed for MEDLINE]
- Overexpression
of p21waf1/cip1 arrests the growth of chicken embryo
fibroblasts that overexpress
E2F1.
Oncogene. 1998 Jun 18;16(24):3115-22.
PMID: 9671390 [PubMed - indexed
for MEDLINE]
- Retroviral
gene delivery.
Methods Cell Biol. 1997;52:179-214. Review. No abstract available.
PMID:
9379950 [PubMed - indexed for MEDLINE]
- Placement
of tRNA primer on the primer-binding site requires pol gene
expression in avian
but not murine retroviruses.
J Virol. 1997 Sep;71(9):6940-6.
PMID: 9261422
[PubMed - indexed for MEDLINE]
- Expression
of a murine leukemia virus Gag-Escherichia coli RNase HI
fusion polyprotein
significantly inhibits virus spread.
J Virol. 1997 Apr;71(4):3312-8.
PMID:
9060701 [PubMed - indexed for MEDLINE]
- Comparative
analysis of the structure and function of the chicken c-myc
and v-myc genes:
v-myc is a more potent inducer of cell proliferation and
apoptosis than c-myc.
Oncogene.
1996 Jun 20;12(12):2611-21.
PMID: 8700520 [PubMed - indexed for MEDLINE]
- Gene
transfer into mammalian cells by a Rous sarcoma virus-based retroviral
vector
with the host range of the amphotropic murine leukemia virus.
J Virol. 1996
Jun;70(6):3922-9.
PMID: 8648729 [PubMed - indexed for MEDLINE]
- Expression
of transduced genes in mice generated by infecting blastocysts
with avian leukosis
virus-based retroviral vectors.
Proc Natl Acad Sci U S A. 1996 May 14;93(10):4931-6.
PMID:
8643506 [PubMed - indexed for MEDLINE]
- Overexpression
of human p21waf1/cip1 arrests the growth of chicken embryo
fibroblasts transformed
by individual oncogenes.
Oncogene. 1995 Dec 21;11(12):2609-18.
PMID: 8545118
[PubMed - indexed for MEDLINE]
- Production
of avian leukosis virus particles in mammalian cells can be mediated
by the
interaction of the human immunodeficiency virus protein Rev and the
Rev-responsive
element.
Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11940-4.
PMID: 8524879
[PubMed - indexed for MEDLINE]
- Replication
of avian leukosis viruses with mutations at the primer binding site:
use of
alternative tRNAs as primers.
J Virol. 1995 Oct;69(10):6228-38.
PMID: 7545245
[PubMed - indexed for MEDLINE]
- Targeting
of a nuclease to murine leukemia virus capsids inhibits viral multiplication.
Proc
Natl Acad Sci U S A. 1995 Jan 17;92(2):364-8.
PMID: 7831291 [PubMed - indexed
for MEDLINE]
- A
system for tissue-specific gene targeting: transgenic mice susceptible to
subgroup
A avian leukosis virus-based retroviral vectors.
Proc Natl Acad Sci U S A.
1994 Nov 8;91(23):11241-5.
PMID: 7972042 [PubMed - indexed for MEDLINE]
- Effects of
the gag region on genome stability: avian retroviral vectors
that contain sequences
from the Bryan strain of Rous sarcoma virus.
Virology. 1994 Sep;203(2):211-20.
PMID:
8053145 [PubMed - indexed for MEDLINE]
- Bcl-2
expressed using a retroviral vector is localized primarily in the nuclear
membrane
and the endoplasmic reticulum of chicken embryo fibroblasts.
Cell Growth Differ.
1994 Apr;5(4):419-29.
PMID: 8043516 [PubMed - indexed for MEDLINE]
- A
new defective retroviral vector system based on the Bryan strain of Rous
sarcoma
virus.
Virology. 1993 Aug;195(2):669-79.
PMID: 8393241 [PubMed - indexed
for MEDLINE]
| 43:
| Salter
DW, Payne WS, Crittenden LB, Federspiel MJ, Petropoulos CJ, Bradac JA,
Hughes
SH. | |
- Avian
leukosis retroviruses and gene transfer into the avian genome.
In Manipulation
of the Avian Genome (RJ Etches and AM Verrinder Gibbins, eds),
CRC Press, pp.
135-150, 1993.
- The
expression of mouse tyrosinase in chick cells in vitro and in vivo when
controlled
by a constitutive promoter.
Pigment Cell Res. 1992 Nov;5(5 Pt 2):312-21.
PMID:
1292014 [PubMed - indexed for MEDLINE]
- Appropriate
in vivo expression of a muscle-specific promoter by using avian
retroviral
vectors for gene transfer [corrected]
J Virol. 1992 Jun;66(6):3391-7.
PMID:
1637416 [PubMed - indexed for MEDLINE]
- Retroviruses
that express different ras mutants cause different types of
tumors in chickens.
Oncogene.
1992 Jan;7(1):141-6.
PMID: 1632878 [PubMed - indexed for MEDLINE]
- Activation
of the c-ski oncogene by overexpression.
J Virol. 1991 Sep;65(9):4929-35.
PMID:
1870207 [PubMed - indexed for MEDLINE]
- Replication-competent
retrovirus vectors for the transfer and expression of
gene cassettes in avian
cells.
J Virol. 1991 Jul;65(7):3728-37.
PMID: 2041092 [PubMed - indexed
for MEDLINE]
- Experimentally
introduced defective endogenous proviruses are highly
expressed in chickens.
J
Virol. 1991 Jan;65(1):313-9.
PMID: 1845892 [PubMed - indexed for MEDLINE]
- Will
retroviral vectors be used to make transgenic livestock?
AgBiotech News Infor.
1991 3:25-8.
- Vectors
and genes for improvement of animal strains.
J Reprod Fertil Suppl. 1990;41:39-49.
Review.
PMID: 2213714 [PubMed - indexed for MEDLINE]
- Expression
of virally-transduced mouse tyrosinase in cultured chick embryo cells.
SAAS
Bull Biochem Biotechnol. 1990 Jan;3:112-7.
PMID: 1369250 [PubMed - indexed
for MEDLINE]
- Expression
of virally transduced mouse tyrosinase in tyrosinase-negative chick
embryo
melanocytes in culture.
Pigment Cell Res. 1989 Nov-Dec;2(6):524-7.
PMID:
2557608 [PubMed - indexed for MEDLINE]
- Helper-independent
retrovirus vectors with Rous-associated virus type O
long terminal repeats.
J
Virol. 1988 Dec;62(12):4809-12.
PMID: 2460645 [PubMed - indexed for MEDLINE]
- Adaptor plasmids
simplify the insertion of foreign DNA into
helper-independent retroviral vectors.
J
Virol. 1987 Oct;61(10):3004-12.
PMID: 3041020 [PubMed - indexed for MEDLINE]
- Transgenic
chickens: insertion of retroviral genes into the chicken germ line.
Virology.
1987 Mar;157(1):236-40.
PMID: 3029962 [PubMed - indexed for MEDLINE]
- Design
of retroviral vectors for the insertion of foreign deoxyribonucleic acid
sequences
into the avian germ line.
Poult Sci. 1986 Aug;65(8):1459-67.
PMID: 3035527
[PubMed - indexed for MEDLINE]
- Gene
insertion into the chicken germ line by retroviruses.
Poult Sci. 1986 Aug;65(8):1445-58.
PMID:
3035526 [PubMed - indexed for MEDLINE]
- Mutation
of a termination codon affects src initiation.
Mol Cell Biol. 1984 Sep;4(9):1738-46.
PMID:
6092936 [PubMed - indexed for MEDLINE]
- Mutagenesis
of the region between env and src of the SR-A strain of
Rous sarcoma virus
for the purpose of constructing helper-independent
vectors.
Virology. 1984
Jul 15;136(1):89-99.
PMID: 6330999 [PubMed - indexed for MEDLINE]
- cis-Acting
RNA packaging locus in the 115-nucleotide direct repeat
of Rous sarcoma virus.
J
Virol. 1983 Dec;48(3):667-75.
PMID: 6313966 [PubMed - indexed for MEDLINE]
- Polypurine
tract adjacent to the U3 region of the Rous sarcoma virus genome
provides a
cis-acting function.
J Virol. 1982 Aug;43(2):482-8.
PMID: 6180180 [PubMed
- indexed for MEDLINE]
- Splicing
of intervening sequences introduced into an infectious retroviral vector.
J
Mol Appl Genet. 1982;1(6):547-59.
PMID: 6296256 [PubMed - indexed for MEDLINE]
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