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Photo of Alan Rein

Head, Retrovirus Assembly Section

HIV Drug Resistance Program
Center for Cancer Research
National Cancer Institute
P.O. Box B, Building 535
Frederick, MD 21702-1201
Phone: 301-846-1361
Fax: 301-846-6013
E-mail: reina@mail.nih.gov


Dr. Alan Rein obtained his Ph.D. with Dr. Harry Rubin at the University of California at Berkeley and did postdoctoral research as an American Cancer Society Fellow under the direction of Dr. Sheldon Penman at the Massachusetts Institute of Technology.  Dr. Rein has been associated with the National Cancer Institute (NCI) since 1976 and served as Head of the Retroviral Genetics Section in the ABL-Basic Research Program from 1984 to 1999.  In 1999, he joined the HIV Drug Resistance Program as Head of the Retrovirus Assembly Section and was appointed to the NCI Senior Biomedical Research Service.  Dr. Rein received the NIH Director's Award in 2012, and in 2014, he was elected a Fellow of the American Academy of Microbiology.  His research has dealt with a number of aspects of the biology and molecular biology of murine and human retroviruses, including virus assembly and maturation, viral envelope function, translational suppression, and pathogenesis.  In 2011, he received a two-year Breast Cancer Research Program grant from the Avon Foundation for Women to support a collaborative project on "Testing for MMTV and Related Retroviruses in Breast Cancer" with Edward Gabrielson, M.D., at Johns Hopkins Medical Institution.  In 2012, Dr. Rein was awarded a three-year Program Grant from the Human Frontier Science Program (HFSP) to support his international collaboration with Bogdan Dragnea, Dmitri Svergun, and Paul Van der Schoot on "Physical Principles in the Self-Assembly of Immature HIV-1 Particles."  Dr. Rein was an Organizer of the 1995 Cold Spring Harbor Laboratory Meeting on Retroviruses and the 2001 International Retroviral Nucleocapsid Symposium.  He currently serves on the Editorial Boards of Virology and Journal of Virology and is a collaborative member of the HIV Interaction and Viral Evolution (HIVE) Center, a consortium of leaders in the field of HIV research who are applying their structural and functional knowledge of drug resistance evolution to the design of more effective anti-HIV treatments.


Last modified: 20 March 2014

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