Beutler, J.A.; McCall, K.L.; Herbert, K.; Johnson, T.; Shoemaker, R.H.; Boyd,M.R.: Phytochemistry 55: 233-236, 2000.
Abstract:
Three novel cytotoxic clerodane diterpene esters, corymbulosins A-C, were isolated from an organic extract of the fruits of Laetia corymbulosa (Flacourtiaceae) from Peru. The structures were determined by spectroscopic methods as clerodane diterpenes unsaturated at C-3, C-13(16) and C-14. Corymbulosin A was esterified at C-2 with a decadienoate moiety, while corymbulosins B and C were C-2 epimers esterified at C-6 with a decanoate moiety.
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