Heidi R. Bokesch, Lewis K. Pannell, Pamela K. Cochran, Raymond C. Sowder II, Tawnya C. McKee, Michael R. Boyd: J.Nat.Prod. 64: 249-250, 2001.
Abstract:
A 37 amino acid cyclic polypeptide has been isolated from the organic extract of the tropical tree Palicourea condensata. Palicourein (1) is the largest of a growing family of plant peptides that contain a cyclized amino acid backbone cross-linked via three internal disulfide bridges. Palicourein inhibits the in vitro cytopathic effects of HIV-1RF infection of CEM-SS cells with an EC50 value of 0.1 µM and an IC50 value of 1.5 µM
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