New cytotoxic isomalabaricane triterpenes from the sponge Jaspis species

Karina M. Meragelman, Tawnya C. McKee, Michael R. Boyd: J.Nat.Prod. 64: 389-392, 2001.

Abstract:

Three new isomalabaricane triterpenes, 29-hydroxystelliferin E (1), 29-hydroxystelliferin A (2) and stelliferin G (3) together with the known triterpene 3-epi-29-hydroxystelliferin E (4), were isolated from the organic extract of the sponge Jaspis sp. collected in the South Pacific. All the compounds isolated showed antiproliferative activity against melanoma cells (MALME-3M).

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