Guttiferone F, the first prenylated benzophenone from Allanblackia stuhlmannii

Richard W. Fuller, John W. Blunt, Jamie L. Boswell, John H. Cardellina II, and Michael R. Boyd: J.Nat.Prod. 62: 130-132, 1999.

Abstract:

The HIV-inhibitory activity in extracts of Allanblackia stuhlmannii was tracked, via bioassay-guided fractionation, to a new member of the camboginol/guttiferone class of prenylated benzophenones, guttiferone F (1). The structure was solved by extensive NMR analyses and by acid-catalyzed conversion to 30-epi-cambogin (4). This is the first report of this compound type in the genus Allanblackia.

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