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Publications


PubMed summary

Google Scholar profile

Complete bibliography (updated April 2019)


Selected Key Publications

Tedbury, P.R., Novikova, M., Ablan, S.D., and Freed, E.O.   (2016)  Biochemical evidence of a role for matrix trimerization in HIV-1 envelope glycoprotein incorporation.  Proc. Natl. Acad. Sci. USA 113: E182-E190.
Abstract     Full-text PDF     Supporting information     PMID 26711999; PMCID PMC4720328
DOI 10.3390/v10110613

Waki, K., Durell, S.R., Soheilian, F., Nagashima, K., Butler, S.L., and Freed, E.O.  (2012)  Structural and functional insights into the HIV-1 maturation inhibitor binding pocket.  PLoS Pathog. 8(11): e1002997.
Abstract     Full-text PDF     Supporting information     PMID 23144615; PMCID PMC3493477
DOI 10.1371/journal.ppat.1002997

Joshi, A., Garg, H., Nagashima, K., Bonifacino, J.S., and Freed, E.O.  (2008)  GGA and Arf proteins modulate retrovirus assembly and release.  Mol. Cell 30: 227-238.
Abstract      Full-text PDF     Supplemental data     PMID 18439901; PMCID PMC2386562
DOI 10.1016/j.molcel.2008.03.015

Ono, A., Ablan, S.D., Lockett, S.J., Nagashima, K., and Freed, E.O.  (2004)  Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane.  Proc. Natl. Acad. Sci. USA 101: 14889-14894.
Abstract      Full-text PDF     Supporting information     PMID 15465916; PMCID PMC522033
DOI 10.1073/pnas.0405596101

Demirov, D.G., Ono, A., Orenstein, J.M., and Freed, E.O.  (2002)  Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function.  Proc. Natl. Acad. Sci. USA 99: 955-960.
Abstract     Full-text PDF     PMID 11805336; PMCID PMC117412
DOI 10.1073/pnas.032511899


Recent Publications

Novikova, M., Adams, L.J., Fontana, J., Gres, A.T., Balasubramaniam, M., Winkler, D.C., Kudchodkar, S.B., Soheilian, F., Sarafianos, S.G., Steven, A.C., and Freed, E.O.  (2018)  Identification of a structural element in HIV-1 Gag required for virus particle assembly and maturation.  mBio 9: e01567-18.
Abstract     Full-text PDF     PMID 30327442; PMCID PMC6191540
DOI 10.1128/mBio.01567-18

Buttler, C.A., Pezeshkian, N., Fernandez, M.V., Aaron, J., Norman, S., Freed, E.O., and Van Engelenburg, S.B.  (2018)  Single molecule fate of HIV-1 envelope reveals late-stage viral lattice formation.  Nat. Commun. 9: 1861.
Abstract     Full-text PDF     Supplementary information
PMID 29748537; PMCID PMC5945595     DOI 10.1038/s41467-018-04220-w

Tedbury, P.R., Novikova, M., Ablan, S.D., and Freed, E.O  (2016)  Biochemical evidence of a role for matrix trimerization in HIV-1 envelope glycoprotein incorporation.  Proc. Natl. Acad. Sci. USA 113: E182-E190.
Abstract     Full-text PDF     Supporting information     PMID 26711999; PMCID PMC4720328
DOI 10.1073/pnas.1516618113

Fontana, J., Keller, P.W., Urano, E., Ablan, S.D., Steven, A.C., and Freed, E.O.  (2016)  Identification of an HIV-1 mutation in spacer peptide 1 that stabilizes the immature CA-SP1 lattice.  J. Virol. 90: 972-978.
Abstract     Full-text PDF     PMID 26537676; PMCID PMC4702660
DOI 10.1128/JVI.02204-15

Martins, A.N., Waheed, A.A., Ablan, S.D., Huang, W., Newton, A., Petropoulos, C.J., Brindeiro, R.M., and Freed, E.O.  (2016)  Elucidation of the molecular mechanism driving duplication of the HIV-1 PTAP late domain.  J. Virol. 90: 768-779.
Abstract     Full-text PDF     PMID 26512081; PMCID PMC4702686
DOI 10.1128/JVI.01640-15

Urano, E., Ablan, S.D., Mandt, R., Pauly, G.T., Sigano, D.M., Schneider, J.P., Martin, D.E., Nitz, T.J., Wild, C.T., and Freed, E.O.  (2016)  Alkyl amine bevirimat derivatives are potent and broadly active HIV-1 maturation inhibitors.  Antimicrob. Agents Chemother. 60: 190-197.
Abstract     Full-text PDF     Supplemental material      PMID 26482309; PMCID PMC4704169
DOI 10.1128/AAC.02121-15

Tedbury, P.R., Mercredi, P.Y., Gaines, C.R., Summers, M.F., and Freed, E.O.  (2015)  Elucidating the mechanism by which compensatory mutations rescue an HIV-1 matrix mutant defective for Gag membrane targeting and envelope glycoprotein incorporation.  J. Mol. Biol. 427: 1413-1427.
Abstract     Full-text PDF     PMID 25659909; PMCID PMC4844178
DOI 10.1016/j.jmb.2015.01.018

Tedbury, P.R., Ablan, S.D., and Freed, E.O.  (2013)  Global rescue of defects in HIV-1 envelope glycoprotein incorporation: Implications for matrix structure.  PLoS Pathog. 9(11): e1003739.
Abstract     Full-text PDF     PMID 24244165; PMCID PMC3828165
DOI 10.1371/journal.ppat.1003739

Checkley, M.A., Luttge, B.G., Mercredi, P.Y., Kyere, S.K., Donlan, J., Murakami, T., Summers, M.F., Cocklin, S., and Freed, E.O.  (2013)  Reevaluation of the requirement for TIP47 in human immunodeficiency virus type 1 envelope glycoprotein incorporation.  J. Virol. 87: 3561-3570.
Abstract     Full-text PDF     PMID 23325685; PMCID PMC3592152
DOI 10.1128/JVI.03299-12

Waki, K., Durell, S.R., Soheilian, F., Nagashima, K., Butler, S.L., and Freed, E.O.  (2012)  Structural and functional insights into the HIV-1 maturation inhibitor binding pocket.  PLoS Pathog. 8(11): e1002997.
Abstract     Full-text PDF     Supporting information     PMID 23144615; PMCID PMC3493477
DOI 10.1371/journal.ppat.1002997


Last modified: 29 April 2019


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