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Publications


PubMed summary


Selected Key Publications

Rawson, J.M.O., Nikolaitchik, O.A., Keele, B.F., Pathak, V.K., and Hu, W.-S.  (2018)  Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity.  Nucleic Acids Res. 46: 10535-10545.
Abstract     Full-text PDF     Supplementary data     PMID 30307534; PMCID PMC6237782
DOI 10.1093/nar/gky910

Chen, J., Rahman, S.A., Nikolaitchik, O.A., Grunwald, D., Sardo, L., Burdick, R.C., Plisov, S., Liang, E., Tai, S., Pathak, V.K., and Hu, W.-S.  (2016)  HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein.  Proc. Natl. Acad. Sci. USA 113: E201-E208.
Abstract     Full-text PDF     Supporting information     PMID 26712001; PMCID PMC4720333
DOI 10.1073/pnas.1518572113

Chen, J., Grunwald, D., Sardo, L., Galli, A., Plisov, S., Nikolaitchik, O.A., Chen, D., Lockett, S., Larson, D.R., Pathak, V.K., and Hu, W.-S.  (2014)  Cytoplasmic HIV-1 RNA is mainly transported by diffusion in the presence or absence of Gag protein.  Proc. Natl. Acad. Sci. USA Plus 111: E5205–E5213.     Abstract     Full-text PDF     Supporting information
PMID 25404326; PMCID PMC4260538     DOI 10.1073/pnas.1413169111

Nikolaitchik, O.A., Dilley, K.A., Fu, W., Gorelick, R.J., Tai, S.-H.S., Soheilian, F., Ptak, R.G., Nagashima, K., Pathak, V.K., and Hu, W.-S.  (2013)  Dimeric RNA recognition regulates HIV-1 genome packaging.  PLoS Pathog. 9(3): e1003249.
Abstract     Full-text PDF     PMID 23555259; PMCID PMC3605237
DOI 10.1371/journal.ppat.1003249

Chen, J., Nikolaitchik, O., Singh, J., Wright, A., Bencsics, C.E., Coffin, J.M., Ni, N., Lockett, S., Pathak, V.K., and Hu, W.-S.  (2009)  High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis.  Proc. Natl. Acad. Sci. USA 106: 13535-13540.     Abstract     Full-text PDF     PMID 19628694; PMCID PMC2714765
DOI 10.1073/pnas.0906822106


Recent Publications

Rawson, J.M.O., Nikolaitchik, O.A., Keele, B.F., Pathak, V.K., and Hu, W.-S.  (2018)  Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity.  Nucleic Acids Res. 46: 10535-10545.
Abstract     Full-text PDF     Supplementary data     PMID 30307534; PMCID PMC6237782
DOI 10.1093/nar/gky910

Dilley, K.A., Nikolaitchik, O.A., Galli, A., Burdick, R.C., Levine, L., Li, K., Rein, A., Pathak, V.K., and Hu, W.-S.  (2017)  Interactions between HIV-1 Gag and viral RNA genome enhance virion assembly.  J. Virol. 91(16): e02319-16.
Abstract      Full-text PDF     PMID 28539452; PMCID PMC5533913
DOI 10.1128/JVI.02319-16

Delviks-Frankenberry, K.A., Nikolaitchik, O.A., Burdick, R.C., Gorelick, R.J., Keele, B.F., Hu, W.-S., and Pathak, V.K.  (2016)  Minimal contribution of APOBEC3-induced G-to-A hypermutation to HIV-1 recombination and genetic variation.  PLoS Pathog. 12(5): e1005646.
Abstract     Full-text PDF     Supporting information
PMID 27186986; PMCID PMC4871359     DOI 10.1371/journal.ppat.1005646

Chen, J., Rahman, S.A., Nikolaitchik, O.A., Grunwald, D., Sardo, L., Burdick, R.C., Plisov, S., Liang, E., Tai, S., Pathak, V.K., and Hu, W.-S.  (2016)  HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein.  Proc. Natl. Acad. Sci. USA 113: E201-E208.
Abstract     Full-text PDF     Supporting information     PMID 26712001; PMCID PMC4720333
DOI 10.1073/pnas.1518572113

Sardo, L., Hatch, S.C., Chen, J., Nikolaitchik, O., Burdick, R.C., Chen, D., Westlake, C.J., Lockett, S., Pathak, V.K., and Hu, W.-S.  (2015)  Dynamics of HIV-1 RNA near the plasma membrane during virus assembly.  J. Virol. 89: 10832-10840.
Abstract     Full-text PDF     PMID 26292321; PMCID PMC4621114
DOI 10.1128/JVI.01146-15

Chen, J., Grunwald, D., Sardo, L., Galli, A., Plisov, S., Nikolaitchik, O.A., Chen, D., Lockett, S., Larson, D.R., Pathak, V.K., and Hu, W.-S.  (2014)  Cytoplasmic HIV-1 RNA is mainly transported by diffusion in the presence or absence of Gag protein.  Proc. Natl. Acad. Sci. USA Plus 111: E5205–E5213.     Abstract     Full-text PDF     Supporting information
PMID 25404326; PMCID PMC4260538     DOI 10.1073/pnas.1413169111

Nikolaitchik, O.A., Dilley, K.A., Fu, W., Gorelick, R.J., Tai, S.-H.S., Soheilian, F., Ptak, R.G., Nagashima, K., Pathak, V.K., and Hu, W.-S.  (2013)  Dimeric RNA recognition regulates HIV-1 genome packaging.  PLoS Pathog. 9(3): e1003249.
Abstract     Full-text PDF     PMID 23555259; PMCID PMC3605237
DOI 10.1371/journal.ppat.1003249

Galli, A., Kearney, M., Nikolaitchik, O.A., Yu, S., Chin, M.P.S., Maldarelli, F., Coffin, J.M., Pathak, V.K., and Hu, W.-S.  (2010)  Patterns of human immunodeficiency virus type 1 recombination ex vivo provide evidence for coadaptation of distant sites, resulting in purifying selection for intersubtype recombinants during replication.  J. Virol. 84: 7651-7661.
Abstract     Full-text PDF     PMID 20504919; PMCID PMC2897624
DOI 10.1128/JVI.00276-10

Moore, M.D., Nikolaitchik, O.A., Chen, J., Hammarskjöld, M.L., Rekosh, D., and Hu, W.-S.  (2009)  Probing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analyses.  PLoS Pathog. 5: e1000627.
Abstract     Full-text PDF     PMID 19834549; PMCID PMC2757677
DOI 10.1371/journal.ppat.1000627

Chen, J., Nikolaitchik, O., Singh, J., Wright, A., Bencsics, C.E., Coffin, J.M., Ni, N., Lockett, S., Pathak, V.K., and Hu, W.-S.  (2009)  High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis.  Proc. Natl. Acad. Sci. USA 106: 13535-13540.     Abstract     Full-text PDF     PMID 19628694; PMCID PMC2714765
DOI 10.1073/pnas.0906822106


Last modified: 25 April 2019


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