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Photo of Vinay Pathak


Head, Viral Mutation Section

HIV Dynamics and Replication Program
Center for Cancer Research
National Cancer Institute
P.O. Box B, Building 535
Frederick, MD 21702-1201
Phone: 301-846-1710
Fax: 301-846-6013
E-mail: pathakv@mail.nih.gov


Dr. Vinay K. Pathak received his B.A. in Biology from the University of California, Los Angeles, in 1979. He obtained his M.S. in Comparative Pathology in 1983 from the University of California, Davis, for characterization of mouse mammary tumor virus proviral integration sites near the int1 and int2 loci in mammary tumors and hyperplastic tissues in Dr. Robert Cardiff's laboratory. He received his Ph.D. for work on characterization of the eukaryotic protein synthesis initiation factors eIF-2a and eIF-2ß in Dr. John W.B. Hershey's laboratory at the University of California, Davis, in 1988. He was a postdoctoral fellow under the guidance of Dr. Howard Temin from 1988 to 1991, where he determined the in vivo forward mutation rate of spleen necrosis virus and characterized the nature of mutations that arise during retroviral replication. These studies were the first to report G-to-A hypermutation in a retrovirus, now known to be the result of cytidine deamination by host restriction APOBEC3 proteins. In 1991, Dr. Pathak became an Assistant Professor in the Department of Biochemistry and the Mary Babb Randolph Cancer Center at West Virginia University. He was promoted to Associate Professor with tenure in 1998. He joined the National Cancer Institute in 1999 as Senior Investigator and Head of the Viral Mutation Section in the HIV Dynamics and Replication Program (renamed as the HIV Dynamics and Replication Program in 2015). Dr. Pathak was appointed as Guest Editor for the "HIV Drug Resistance" special issue of Viruses, published in 2010. In 2012, he received the NIH Asian and Pacific Islander American Organization Award for outstanding accomplishments in biomedical research. He served as Co-Chair (2013-2014) and Chair (2015) of the Annual Norman P. Salzman Memorial Symposium in Virology, NIH. In 2017, he served as Co-Organizer of the Cold Spring Harbor Laboratory Retroviruses Meeting. He currently serves as a member of the NCI RNA Biology Initiative.

Arrowhead pointing to right Dr. Pathak Served as Co-Organizer of 2017 Retroviruses Meeting

Arrowhead pointing to right Dr. Pathak Received NIH Asian & Pacific Islander American Organization Award

Arrowhead pointing to right Report on De-Discovery of the Retrovirus XMRV Designated a Fast Breaking Paper
   by Science Watch in 2012 and Selected as a Top CCR Science Advance in 2011

Arrowhead pointing to right Dr. Pathak Appointed as Guest Editor for Viruses

Arrowhead pointing to right Pathak Figure from HIV DRP Home Page



Last modified: 13 June 2017

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