The central figure on the home page depicts a cross section of a retroviral virion, surrounded by images representing the research interests of the HIV Dynamics and Replication Program (HIV DRP). The oval images around the virion link to the home pages of the Program's senior scientific staff (clockwise from the top):
Three-dimensional structures of the following virion proteins are shown along the left side of HIV DRP home page:
(from the top) reverse transcriptase; protease; integrase; the Gag proteins nucleocapsid,
capsid, and matrix; and the gp120 envelope protein. The colors of the structures
correspond to the colors of the same components shown in the virion.
The illustrations of the virion and all of the individual proteins except nucleocapsid and envelope were modified from those on the cover of the book Retroviruses, edited by John M. Coffin, Stephen H. Hughes, and Harold E. Varmus, 1997, Cold Spring Harbor Laboratory Press (permission granted from the publisher). The illustrations of the nucleocapsid and envelope proteins were derived from information available through Protein Data Bank accession numbers 1A1T and 1GC1, respectively.
Last modified: 15 October 2018