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Recent HIV DRP Publications (July–November 2018)*


Achuthan, V., Perreira, J.M., Sowd, G.A., Puray-Chavez, M., McDougall, W.M., Paulucci-Holthauzen, A., Wu, X., Fadel, H.J., Poeschla, E.M., Multani, A.S., Hughes, S.H., Sarafianos, S.G., Brass, A.L., and Engelman, A.N. (2018) Capsid-CPSF6 interaction licenses nuclear HIV-1 trafficking to sites of viral DNA integration. Cell Host Microbe 24: 392-404.
Abstract     Full-text PDF     PMID 30173955     DOI 10.1016/j.chom.2018.08.002

Anderson, E.M., and Maldarelli, F. (2018) Quantification of HIV DNA using droplet digital PCR techniques. Curr. Protoc. Microbiol. 51: e62.
Abstract     Full-text PDF     PMID 30253074; PMCID PMC6209535
DOI 10.1002/cpmc.62

Anderson, E.M., and Maldarelli, F. (2018) The role of integration and clonal expansion in HIV infection: Live long and prosper. Retrovirology 15: 71.
Abstract     Full-text PDF     PMID 30352600; PMCID PMC6199739
DOI 10.1186/s12977-018-0448-8

Cohen, S.E., Sachdev, D., Lee, S., Scheer, S., Bacon, O., Chen, M.-J., Okochi, H., Anderson, P.L., Kearney, M.F., Coffey, S., Scott, H., Grant, R., Havlir, D., and Gandhi, M. (2018) Acquisition of tenofovir-susceptible HIV despite consistently high level adherence to daily PrEP as measured by plasma, dried blood spot (DBS) and segmental hair analysis: A case report. Lancet HIV, in press.

Comas-Garcia, M., Kroupa, T., Datta, S.A.K., Harvin, D.P., Hu, W.-S., and Rein, A. (2018) Efficient support of virus-like particle assembly by the HIV-1 packaging signal. eLife 7: e38438.
Abstract     Full-text PDF     PMID 30070634; PMCID PMC6092119
DOI 10.7554/eLife.38438

Fernandez, M.V., and Freed, E.O. (2018) Meeting review: 2018 International Workshop on Structure and Function of the Lentiviral gp41 Cytoplasmic Tail. Viruses 10: 613.
Abstract    Full-text PDF     PMID 30405009    DOI 10.3390/v10110613

Grossman, Z., Rico, S., Cone, K., Shao, W., Rehm, C., Jones, S., Bozzi, G., Dean, S., Dewar, R., Rehman, T., Purdy, J., Hadigan, C., Pau, A.K., and Maldarelli, F. (2018) Early presence of HIV-1 subtype C in Washington, D.C. AIDS Res. Hum. Retroviruses 34: 680-684.
Abstract     Full-text PDF     Supplemental material     PMID 29936863; PMCID PMC6080110
DOI 10.1089/AID.2018.0041

Novikova, M., Adams, L.J., Fontana, J., Gres, A.T., Balasubramaniam, M., Winkler, D.C., Kudchodkar, S.B., Soheilian, F., Sarafianos, S.G., Steven, A.C., and Freed, E.O. (2018) Identification of a structural element in HIV-1 Gag required for virus particle assembly and maturation. mBio 9: e01567-18.
Abstract     Full-text PDF     PMID 30327442; PMCID PMC6191540
DOI 10.1128/mBio.01567-18

Rawson, J.M.O., Nikolaitchik, O.A., Keele, B.F., Pathak, V.K., and Hu, W.-S. (2018) Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity. Nucleic Acids Res. 46: 10535-10545.
Abstract     Full-text PDF     Supplementary data     PMID 30307534
DOI 10.1093/nar/gky910

Roth, T.L., Puig-Saus, C., Yu, R., Shifrut, E., Carnevale, J., Li, P.J., Hiatt, J., Saco, J., Krystofinski, P., Li, H., Tobin, V., Nguyen, D.N., Lee, M.R., Putnam, A.L., Ferris, A.L., Chen, J.W., Schickel, J.N., Pellerin, L., Carmody, D., Alkorta-Aranburu, G., Del Gaudio, D., Matsumoto, H., Morell, M., Mao, Y., Cho, M., Quadros, R.M., Gurumurthy, C.B., Smith, B., Haugwitz, M., Hughes, S.H., Weissman, J.S., Schumann, K., Esensten, J.H., May, A.P., Ashworth, A., Kupfer, G.M., Greeley, S.A.W., Bacchetta, R., Meffre, E., Roncarolo, M.G., Romberg, N., Herold, K.C., Ribas, A., Leonetti, M.D., and Marson, A. (2018) Reprogramming human T cell function and specificity with non-viral genome targeting. Nature 559: 405-409.
Abstract     Full-text PDF     PMID 29995861; PMCID PMC6239417
DOI 10.1038/s41586-018-0326-5

Shi, G., Ozog, S., Torbett, B.E., and Compton, A.A. (2018) mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc. Natl. Acad. Sci. USA 115: E10069-E10078. Abstract     Full-text PDF     PMID 30301809; PMCID PMC6205447
DOI 10.1073/pnas.1811892115

Smith, S.J., Zhao, X.Z., Burke, T.R., Jr., and Hughes, S.H. (2018) HIV-1 integrase inhibitors that are broadly effective against drug-resistant mutants. Antimicrob. Agents Chemother. 62: e01035-18.
Abstract     Full-text PDF     PMID 29987149; PMCID PMC6125528
DOI 10.1128/AAC.01035-18

Uhl, J., Gujarathi, S., Waheed, A.A., Gordon, A., Freed, E.O., and Gousset, K. (2018) Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes. J. Cell Commun. Signal., in press.
Abstract    PMID 30443895     DOI 10.1007/s12079-018-0493-z

Van Duyne, R., and Freed, E.O. (2018) HIV-1 packs in PACSIN2 for cell-to-cell spread. Proc. Natl. Acad. Sci. USA 115: 6885-6887.
PubMed citation     Full-text PDF     PMID 29925599; PMCID PMC6142252
DOI 10.1073/pnas.1808821115


*Disclaimer: Links to these publications are provided as a service to visitors of the HIV Dynamics and Replication Program (HIV DRP) website. The HIV DRP is not responsible for the availability or content of these external sites, nor does the HIV DRP endorse, warrant, or guarantee the products, services, or information described or offered at these other sites.

Last modified: 19 November 2018


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