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Recent HIV DRP Publications (June–September 2020)*

Brown, J.B., Summers, H.R., Brown, L.A., Marchant, J., Canova, P.N., O’Hern, C.T., Abbott, S.T., Nyaunu, C., Maxwell, S., Johnson, T., Moser, M.B., Ablan, S.D., Carter, H., Freed, E.O.*, and Summers, M.F.*  (2020)  Structural and mechanistic studies of the rare myristoylation signal of the feline immunodeficiency virus.  J. Mol. Biol. 432: 4076-40919.  (*Joint corresponding author)
Abstract     Full-text PDF     PMID 32442659     DOI 10.1016/j.jmb.2020.05.008

Fernandez, M.V., Hoffman, H.K., Pezeshkian, N., Tedbury, P.R., van Engelenburg, S.B., and Freed, E.O.  (2020)  Elucidating the basis for permissivity of the MT-4 T-cell line to replication of an HIV-1 mutant lacking the gp41 cytoplasmic tail.  J. Virol., in press September 16.
Abstract     Full-text PDF     PMID 32938764     DOI 10.1128/JVI.01334-20

He, S., Hetrick, B., Dabbagh, D., Akhrymuk, I.V., Kehn-Hall, K., Freed, E.O., and Wu, Y.  (2020)  PSGL-1 blocks SARS-CoV-2 S protein-mediated virus attachment and infection of target cells. bioRxiv 2020.05.01.073387.
Abstract     Full-text PDF     PMID 32511349; PMCID PMC7255790
DOI 10.1101/2020.05.01.073387

Kleinpeter, A.B., and Freed, E.O.  (2020)  HIV-1 maturation: Lessons learned from inhibitors.  Viruses 12: 940.
Abstract     Full-text PDF     PMID 32858867     DOI 10.3390/v12090940

Liu, D., Ndongwe, T.P., Puray-Chavez, M., Casey, M.C., Izumi, T., Pathak, V.K., Tedbury, P.R., and Sarafianos, S.G.  (2020)  Effect of P-body component Mov10 on HCV virus production and infectivity.  FASEB J. 34: 9433-9449.
Abstract     Full-text PDF     PMID 32496609     DOI 10.1096/fj.201800641R

Mitchell, J.L., Takata, H., Muir, R., Colby, D.J., Kroon, E., Crowell, T.A., Sacdalan, C., Pinyakorn, S., Puttamaswin, S., Benjapornpong, K., Trichavaroj, R., Tressler, R.L., Fox, L., Polonis, V.R., Bolton, D.L., Maldarelli, F., Lewin, S.R., Haddad, E.K., Phanuphak, P., Robb, M.L., Michael, N.L., de Souza, M., Phanuphak, N., Ananworanich, J., Trautmann, L, and RV397, RV411, and RV254 Study Groups.  (2020)  Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption.  J. Clin. Invest. 130: 2845-2858.
Abstract     Full-text PDF    PMID 32017709; PMCID PMC7260031
DOI 10.1172/JCI130597

Nikolaitchik, O.A., Somoulay, X., Rawson, J.M.O., Yoo, J.A., Pathak, V.K., and Hu, W.-S.  (2020)  Unpaired guanosines in the 5' untranslated region of HIV-1 RNA act synergistically to mediate genome packaging.  J. Virol., in press August 12.
Abstract     Full-text PDF     PMID 32796062    DOI 10.1128/JVI.00439-20

Rausch, J.W., Capoferri, A.A., Katusiime, M.G., Patro, S.C., and Kearney, M.F.  (2020)  Low genetic diversity may be an Achilles heel of SARS-CoV-2.  Proc. Natl. Acad. Sci. USA, in press September 21.
Full-text PDF    PMID 32958678     DOI 10.1073/pnas.2017726117

Rein, A.  (2020)  The heart of the HIV RNA packaging signal?  Proc. Natl. Acad. Sci. USA 117: 19621-19623.
Full-text PDF    PMID 32723818    DOI 10.1073/pnas.2013378117

Sarni, S., Biswas, B., Liu, S., Olson, E.D., Kitzrow, J.P., Rein, A., Wysocki, V.H., and Musier-Forsyth, K.  (2020)  HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal.  J. Biol. Chem., in press August 13.
Abstract     Full-text PDF    PMID 32817318     Supporting information
DOI 10.1074/jbc.RA120.014835

Shao, W., Boltz, V.F., Hattori, J., Bale, M.J., Maldarelli, F., Coffin, J.M., and Kearney, M.F.  (2020)  HIV-DRLink: A tool for reporting linked HIV-1 drug resistance mutations in large single-genome datasets using the Stanford HIV Database.  AIDS Res. Human Retroviruses, in press July 19.
Abstract     Full-text PDF    PMID 32683881     DOI 10.1089/AID.2020.0109

Shi, G., Kenney, A.D., Kudryashova, E., Zhang, L., Hall-Stoodley, L., Robinson, R.T., Kudryashov, D.S., Compton, A.A., and Yount, J.S.  (2020)  Opposing activities of IFITM proteins in SARS-CoV-2 infection.  bioRxiv 2020.08.11.246678.
Abstract     Full-text PDF    PMID 32803197; PMCID PMC7427135
DOI 10.1101/2020.08.11.246678

Smith, S.J., Pauly, G.T., Hewlett, K., Schneider, J.P., and Hughes, S.H..  (2020)  Structure-based non-nucleoside inhibitor design: Developing inhibitors that are effective against resistant mutants.  Chem. Biol. Drug Des., in press August 2.
Abstract     Full-text PDF    PMID 32743937     DOI 10.1111/cbdd.13766

Smith, S.J., Zhao, X.Z., Passos, D.O., Lyumkis, D., Burke, T.R., Jr., and Hughes, S.H..  (2020)  HIV-1 integrase inhibitors that are active against drug-resistant integrase mutants.  Antimicrob. Agents Chemother. 64: e00611-29.
Abstract     Full-text PDF    PMID 32601157     DOI 10.1128/AAC.00611-20

Spinelli, M.A., Lowery, B., Shuford, J.A., Spindler, J., Kearney, M.F., McFarlane, J.R., McDonald, C., Okochi, H., Phung, N., Kuncze, K., Jee, K., Johannessen, D., Anderson, P.L., Smith, D.K., Defechereux, P., Grant, R.M., and Gandhi, M.  (2020)  Use of drug-level testing and single-genome sequencing to unravel a case of HIV seroconversion on PrEP.  Clin. Infect. Dis., in press July 20.
Abstract     Full-text PDF    PMID 32686825     DOI 10.1093/cid/ciaa1011

*Disclaimer:  Links to these publications are provided as a service to visitors of the HIV Dynamics and Replication Program (HIV DRP) website.  The HIV DRP is not responsible for the availability or content of these external sites, nor does the HIV DRP endorse, warrant, or guarantee the products, services, or information described or offered at these other sites.

Last modified: 21 September 2020

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