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Recent HIV DRP Publications (June–September 2019)*

Alfadhli, A., Staubus, A.O., Tedbury, P.R., Novikova, M., Freed, E.O., and Barklis, E.  (2019)  Analysis of HIV-1 matrix-envelope cytoplasmic tail interactions.  J. Virol., in press (Aug 2 Epub ahead of print).
Abstract     Full-text PDF    PMID 31375589     DOI 10.1128/JVI.01079-19

Boltz, V.F., Shao, W., Bale, M.J., Halvas, E.K., Luke, B., McIntyre, J.A., Schooley, R.T., Lockman, S., Currier, J.S., Sawe, F., Hogg, E., Hughes, M.D., Kearney, M.F., Coffin, J.M., and Mellors, J.W.  (2019)  Linked dual-class HIV resistance mutations are associated with treatment failure.  J. Clin. Invest. Insight, in press (Sept 5 Epub ahead of print).
Abstract     Full-text PDF    PMID 31487271     DOI 10.1172/jci.insight.130118

Coffin, J.M., Wells, D., Zerbato, J.M., Kuruc, J.D., Guo, S., Luke, B.T., Eron, J.J., Bale, M., Spindler, J., Simonetti, F.R., Hill, S., Kearney, M.F., Maldarelli, F., Wu, X., Mellors, J.W., and Hughes, S.H.  (2019)  Clones of infected cells arise early in HIV infected individuals.  JCI Insight 4: e128432.
Abstract     Full-text PDF     PMID 31217357; PMCID PMC6629130
DOI 10.1172/jci.insight.128432

Related video:

Coffin, J., and Hughes, S.H.  Author's Take — Persistence of early arising clones of HIV-infected cells in patients.  JCI Insight, published July 3, 2019.

Ferris, A.L., Wells, D.W., Guo, S., Del Prete, G.Q., Swanstrom, A.E., Coffin, J.M., Wu, X., Lifson, J.D., and Hughes, S.H.  (2019)  Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans. PLoS Pathog. 15: e1007869.
Abstract     Full-text PDF     PMID 31291371; PMCID PMC6619828
DOI 10.1371/journal.ppat.1007869

Grossman, Z., Avidor, B., Girshengoren, S., Katchman, E., Maldarelli, F., and Turner, D.  (2019)  Transmission dynamics of HIV subtype A in Tel Aviv, Israel: Implications for HIV spread and eradication.  Open Forum Infect. Dis. 6(7): ofz304.
Abstract     Full-text PDF     PMID 31363777; PMCID PMC6657966     DOI 10.1093/ofid/ofz304

Mailler, E., Waheed, A.A., Park, S.Y., Gershlick, D.C., Freed, E.O., and Bonifacino, J.S.  (2019)  The autophagy protein ATG9A promotes HIV-1 infectivity.  Retrovirology 16: 18.
Abstract     Full-text PDF     PMID 31269971; PMCID PMC6607583
DOI 10.1186/s12977-019-0480-3

McManus, W.R., Bale, M.J., Spindler, J., Wiegand, A., Musick, A., Patro, S.C., Sobolewski, M.D., Musick, V.K., Anderson, E.M., Cyktor, J.C., Halvas, E.K., Shao, W., Wells, D., Wu, X., Keele, B.F., Milush, J.M., Hoh, R., Mellors, J.W., Hughes, S.H., Deeks, S.G., Coffin, J.M., and Kearney, M.F.  (2019)  HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy.  J. Clin. Invest. 130: 126714.
Abstract      Full-text PDF     PMID 31361603     DOI 10.1172/JCI126714

Musick, A., Spindler, J., Boritz, E., Perez, L., Crespo-Velez, D., Patro, S.C., Sobolewski, M.D., Bale, M.J., Reid, C., Keele, B.F., Shao, W., Wiegand, A., Simonetti, F.R., Mellors, J.W., Hughes, S.H., Coffin, J.M., Maldarelli, F., and Kearney, M.F.  (2019)  HIV infected T cells can proliferate in vivo without inducing expression of the integrated provirus.  Front. Microbiol., in press.

O’Doherty, U., and Freed, E.O.  (2019)  News & views: Heavy metal protease takes a tiki torch to HIV assembly.  Nat. Immunol. 20: 668–669.
Abstract     Full-text PDF     PMID 31061529      DOI 10.1038/s41590-019-0387-0

Ozog, S., Timberlake, N.D., Hermann, K., Garijo, O., Haworth, K.G., Shi, G., Glinkerman, C.M., Schefter, L.E., D'Souza, S., Simpson, E., Sghia-Hughes, G., Carillo, R.R., Boger, D.L., Kiem, H.P., Slukvin, I., Ryu, B.Y., Sorrentino, B.P., Adair, J.E., Snyder, S.A., Compton, A.A., and Torbett, B.E.  (2019)  Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes.  Blood, in press (Aug 15 Epub ahead of print).
Abstract     Full-text PDF     PMID 31416800      DOI 10.1182/blood.2019000040

Rein, A.  (2019)  RNA packaging in HIV.  Trends Microbiol. 27: 715-723.
Abstract     Full-text PDF     PMID 31085095     DOI 10.1016/j.tim.2019.04.003

Shah, N.N., Qin, H., Yates, B., Su, L., Shalabi, H., Raffeld, M., Ahlman, M.A., Stetler-Stevenson, M., Yuan, C., Guo, S., Liu, S., Hughes, S.H., Fry, T.J., and Wu, X.  (2019)  Clonal expansion of CAR T cells harboring lentivector integration in the CBL gene following anti-CD22 CAR T-cell therapy.  Blood Adv. 3: 2317-2322.
Full-text PDF     PMID 31387880; PMCID PMC6693002
DOI 10.1182/bloodadvances.2019000219

Shao, W., Shan, J., Hu, W.-S., Halvas, E.K., Mellors, J.W., Coffin, J.M., Kearney, M.F.  (2019)  HIV Proviral Sequence Database (PSD): A new public database for near full-length HIV proviral sequences and their meta-analyses.  AIDS Res. Hum. Retroviruses, in press (Sept 10 Epub ahead of print).
Abstract     Full-text PDF     DOI 10.1089/AID.2019.0214

Uhl, J., Gujarathi, S., Waheed, A.A., Gordon, A., Freed, E.O., and Gousset, K.  (2019)  Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes.  J. Cell Commun. Signal. 13: 209-224.
Abstract     Full-text PDF     PMID 30443895; PMCID PMC6498342
DOI 10.1007/s12079-018-0493-z

Winchester, N.E., Maldarelli, F., Mejia, Y., Dee, N., Dewar, R., Laidlaw, E., Kuriakose, S.S., Stoll, P., Proschan, M., Lane, H.C., and Pau, A.K.  (2019)  8-day inpatient directly observed therapy for ART failure: A tool for preventing unnecessary ART changes and optimizing adherence support.  Clin. Infect. Dis., in press (Jul 11 Epub ahead of print).
Abstract     PMID 31217357     DOI 10.1093/cid/ciz590

*Disclaimer:  Links to these publications are provided as a service to visitors of the HIV Dynamics and Replication Program (HIV DRP) website.  The HIV DRP is not responsible for the availability or content of these external sites, nor does the HIV DRP endorse, warrant, or guarantee the products, services, or information described or offered at these other sites.

Last modified: 10 September 2019

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